Tyrosol, the Major Olive Oil Biophenol, Protects Against Oxidized-LDL-Induced Injury in Caco-2 Cells

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Hydroxytyrosol and tyrosol sulfate metabolites protect against the oxidized cholesterol pro-oxidant effect in Caco-2 human enterocyte-like cells.

The aim of this study was to investigate the ability of the sulfate metabolites of hydroxytyrosol (HT) and tyrosol (TYR) to act as antioxidants counteracting the pro-oxidant effect of oxidized cholesterol in intestinal cells. For this purpose, we synthesized sulfate metabolites of HT and TYR using a chemical methodology and examined their antioxidant activity in Caco-2 monolayers in comparison ...

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ژورنال

عنوان ژورنال: The Journal of Nutrition

سال: 1999

ISSN: 0022-3166,1541-6100

DOI: 10.1093/jn/129.7.1269